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Gunning Group

Gunning Group

🔄 Data last refreshed 2 days ago
🤝

Make a deal with Gunning Group

🔒 Paid proposals held safely in escrow — released only when the work's approved.

Every booking is a normal escrow-protected deal.

Followers
135
Account age
3 yrs
🎁 Free analysisfor Gunning Group

Known for

📊 Post engagement

5
Avg engagement / post
3.7%
Engagement vs followers
Dec 2022
On Mastodon since

🔥 Top post: An exciting new paper by researchers at Genentech led by Erin Du · 15 likes + reposts

📊 Activity & format

Posting cadence
0.18 / week
A lower-frequency account — each post lands with more weight.
Content mix
Mostly text
Recent: 9 text · 3 image · 0 video.
Follower / following
0.7×
Follows 202 back. A more reciprocal / networked account.
🔥 Top post An exciting new paper by researchers at Genentech led by Erin Dueber describes a ligase-agnostic #TargetedProteinDegradation platform based on direct 26S proteasome recruitment with macrocyclic PSMD2 ligands! Clever use of the D-enantiomeric macrocycle as an inactive control. Th… ★ 15
Thrilled to share our #OpenAccess online resource "An Introduction to Medicinal Chemistry & Molecular Recognition" on @OpenLibraryON! We designed this resource to provide budding medicinal chemists with the knowledge & tools to navigate sm… Check out our preprint on an #AI-powered #ligandability prediction platform for bottom-up analysis of #chemoproteomic data to identify #covalent binding sites, including cryptic sites, for the discovery of novel drug targets. #proteomics #… Thrilled to share our story on the first rationally designed #covalent #HDAC inhibitor! YSR734 uses an SNAr-reactive electrophile to engage a noncatalytic nitrosylation site cysteine in #HDAC2, showing in vitro activity in AML & #DuchenneM… ★ 3 #Job alert! We're #hiring a Laboratory Technician at the Centre for Medicinal Chemistry (#CMC) @UTM ! Join the forefront of small-molecule therapeutic discovery as an integral member of our team! Learn more and apply by Nov 28 here: https:… ★ 2 The Centre for Medicinal Chemistry (CMC) at @UTM is hiring an Administrative Assistant! For more information or to apply, read the full job posting here: https://jobs.utoronto.ca/job/Mississauga-Administrative-Assistant-ON/575276617/ The mystery of @genentech's monovalent BRD degraders equipped with a propargyl "degradation tail" has been solved by researchers @abbvie: a #CRISPR screen reveals molecular glue-like recruitment of #DCAF16. #TargetedProteinDegradation #Mon… ★ 1 Granted, the test case is—you guessed it—#BRD4. Nevertheless, this could be an exciting new #TPD modality if it is generalizable to other target proteins, such as those lacking accessible lysines or for which #ubiquitination is slow or ine… ★ 2 And it's wonderful to see that our alumnus Gary Tin and the amazing Georg Winter wrote the News & Views piece on this paper! #gunningalumni https://www.nature.com/articles/s41589-022-01217-x ★ 2 Interesting work by Samy Meroueh @IUMedSchool on the development and characterization of reversible #covalent cyanamide antagonists of TEAD-YAP1 that engage a conserved cysteine palmitoylation site in #TEAD. https://pubs.acs.org/doi/abs/1… ★ 2 Feel free to give us a follow here (or on the bird site @gunninglabuoft) to keep up with the latest research and news from our group and to see posts about cool new papers in #medchem, #chemicalbiology, and #drugdiscovery! ★ 6 Our recent work has focused on the development of small-molecule inhibitors for #HDAC enzymes as well as the "undruggable" transcription factors #STAT3 and #STAT5 as potential treatments for hematological malignancies and other cancers. h… ★ 12

🐘 Community & instance

Home server
mstdn.science
Their home server on the fediverse — the instance a creator picks signals the community they belong to.
On Mastodon since
Dec 2022
Joined in the Twitter-exodus wave of late 2022 — part of the migration that made Mastodon a real destination.

💡 Facts

🗓️Joined Mastodon in 2022 — 3 years ago.
👁️Averages 5 views per post.
📤Posts about 0.2× per week.

🕵️ Fake follower check

Estimated
80/100
Excellent Credibility score
97%
Real Real audience
Low Fake-follower risk
High Data confidence
  • Est. 97% real, active audience · Low fake-follower risk.
  • Strong engagement (~3.7% of followers engage each post) — an active, real audience.
  • Established account (3+ years old).

Heuristic estimate from engagement, follower ratios, account age & growth — a screening signal, not a guarantee.

About

Multidisciplinary team of molecular architects using #medicinalchemistry & #molecularrecognition to design better medicines. Led by Prof. Patrick Gunning, Centre for Medicinal Chemistry, University of Toronto Mississauga #HDAC #STAT3 #STAT5 #MedicinalChemistry #ChemicalBiology #DrugDiscovery #CovalentInhibitors #TargetedProteinDegradation #Chemistry #ChemistryMastodon #ScienceMastodon #Chemiverse #ChemToots

📸 Gallery

Frequently asked questions

How much does Gunning Group charge for a sponsorship?
Gunning Group hasn't published fixed prices yet. Send a proposal through SocialDB and agree terms directly — your payment is held in escrow until the work is approved.
How do I contact Gunning Group for a brand deal or collaboration?
Send a paid deal or collab request right here on SocialDB — we notify Gunning Group, and once they accept, your payment is held safely in escrow and released when the work is approved. You don't need to track down an email.
How many followers does Gunning Group have?
Gunning Group has 135 followers on Mastodon.

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